Addicted to one-night stands or dependent on one another?
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
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The moment that still lives in your head.
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Jake Gyllenhaal
Jamie Randall
Anne Hathaway
Maggie Murdock
Oliver Platt
Bruce Winston
Hank Azaria
Dr. Stan Knight
Josh Gad
Josh Randall
Gabriel Macht
Trey Hannigan
Judy Greer
Cindy
Jill Clayburgh
Nancy Randall
George Segal
Dr. James Randall
Kate Jennings Grant
Gina
Katheryn Winnick
"Lisa"
Kimberly Scott
Gail
Peter Friedman
California Man
Nikki DeLoach
Christy
Natalie Gold
Dr. Helen Randall
Edward Zwick
Director
Edward Zwick
Screenplay
Marshall Herskovitz
Screenplay
Charles Randolph
Screenplay
Arnon Milchan
Executive Producer
Margaret Riley
Executive Producer
Edward Zwick
Producer
Marshall Herskovitz
Producer
Charles Randolph
Producer
Pieter Jan Brugge
Producer
Scott Stuber
Producer
Noam Dromi
Producer
Steven Fierberg
Director of Photography
James Newton Howard
Original Music Composer
Steven Rosenblum
Editor
