Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.
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Dwayne Johnson
Frank Wolff
Emily Blunt
Dr. Lily Houghton
Edgar Ramírez
Lope de Aguirre
Jack Whitehall
McGregor Houghton
Jesse Plemons
Prince Joachim
Paul Giamatti
Nilo Nemolato
Veronica Falcón
Trader Sam
Dani Rovira
Sancho
Quim Gutiérrez
Melchor
Dan Dargan Carter
Gonzalo
Andy Nyman
Sir James Hobbs-Coddington
Raphael Alejandro
Zaqueu
Simone Lockhart
Anna
Pedro Lopez
Chief
Sulem Calderon
Quila
Jaume Collet-Serra
Director
Michael Green
Screenplay
Glenn Ficarra
Screenplay
John Requa
Screenplay
Douglas C. Merrifield
Executive Producer
Scott Sheldon
Executive Producer
Dwayne Johnson
Producer
John Davis
Producer
Dany Garcia
Producer
Hiram Garcia
Producer
John Fox
Producer
Beau Flynn
Producer
Flavio Martínez Labiano
Director of Photography
James Newton Howard
Original Music Composer
Joel Negron
Editor
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